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Mild hyperhomocysteinemia levels are seen in about 5%-12% of the general population. In specific populations such as, alcoholics (due to poor vitamin intake) or patients with chronic kidney disease, this may be more common. The severe genetic form, ... more
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PURPOSE: The arteriole-to-venule ratio (AVR) is widely used for investigating subclinical cerebral microangiopathy. The possible occurrence of retinal vascular caliber changes was investigated in a population of hyperhomocysteinaemic (plasma total ... more
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Hyperhomocysteinemia is a blood disorder marked by an excess amount of the amino acid homocysteine in the blood stream. While healthy levels of homocysteine in the blood are thought to help regulate metabolism and insulin absorption, high levels of ... more
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Original article Roblin X et al. (2007) Hyperhomocysteinaemia is associated with osteoporosis in patients with Crohn's disease. Aliment Pharmacol Ther 25: 797–804 PubMedLow bone mineral density (BMD) and osteoporosis are frequently found in ... more
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Hyperhomocysteinemia is the consequence of impaired methionin metabolism, usually due to a deficiency in cystathionine b-synthase. It is associated with premature cerebral, peripheral and coronary vascular disease for several years but the strength ... more
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Low serum vitamin B12, or genetic defect in uptake or utilization of B12 proteins, such as an intrinsic factor deficiency, can lead to a condition known as hyperhomocysteinemia, a condition in which there is an over-excess of homocysteine in the ... more
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