A patient presents with an undifferentiated metastasis and past medical history indicates two independent primary tumors. Can molecular diagnostics help identify the origin of the metastatic deposit?
In some instances, “molecular fingerprints” that can be attributed to a given histological type can unequivocally help establish the origin of a metastasis. This approach can be used not only for sorting out the origin of a secondary deposit, but also for differentiating a metastasis from a “second primary.
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