A six year old girl is found to have mild mental retardation, bilateral limb defects (polydactyly), and a congenital heart defect. Which of the following categories of disease is LEAST likely?

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A six year old girl is found to have mild mental retardation, bilateral limb defects (polydactyly), and a congenital heart defect. Which of the following categories of disease is LEAST likely?

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A. Single gene disorder B. Chromosomal disorder C. Polygenic disorder D. Multifactorial disorder E. All of the above are possibilities, and should be considered in the diagnosis of this patient.