Anxiety and/or agitation have been associated with the administration of Clolar. How should this be managed?
Some pediatric patients may experience restlessness, agitation, and anxiety during the infusion. If this occurs, immediately slow the infusion and inform the oncologist. Anxiolytics and/or antihistamines have been used to control anxiety during Clolar infusions. In some patients, premedication with an antianxiety agent may be considered prior to the next dose.
