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Are any alpha-2 antagonists available in the current market?

April 26, 2017alpha-2 antagonists market

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Are any alpha-2 antagonists available in the current market?

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Atimpamezole is an intravenous alpha-2 antagonist that appears to be capable of reversing the sedative effects of Dex [i]. However, this agent is approved only for veterinary use in the US as a reversal agent for medetomidine. It is marketed by Pfizer, Inc. under the trade name Antisedan®. There is no known human development program at this time for atipamezole. Other alpha-2 adrenergic antagonists include idazoxan, yohimbine, efaroxan, and rauwolscine; of these, only yohimbine is marketed in the US where it is used as an aphrodisiac.