Are differential equations the only type of mathematics used in Archimedes?
Other formulas describe the clinical, logistical and economic events that are set in motion by the symptoms and outcomes of each person’s disease. These formulas are typical of regression models, decision trees, flow charts, and accounting models. All the formulas can include person-to-person differences, random variations, and uncertainty. Because Archimedes is a simulation model that follows thousands of patients, its results are subject to random variations and sampling like those of a real clinical trial. Q: Where does Archimedes get its data? A: Information about the demographics of the simulated members comes from large, existing administrative data sets. Information about risk factors for diseases is obtained from epidemiological studies, such as the Framingham heart study. Models of the biology of the diseases are based on known physiology. Information about the effects of different treatments is obtained from clinical research. Information about personnel, facilities and logis
