Are men using finasteride for BPH at risk for developing high-grade prostate cancer?
All men are at risk for developing prostate cancer, and some men will develop high-grade disease whether or not they use finasteride. In the PCPT, 5.1 percent of all men taking the placebo developed high-grade prostate cancer, and 6.4 percent of all men taking finasteride developed high-grade prostate cancer. Men taking finasteride for BPH should talk with their physicians about the PCPT study results and about their risk for developing prostate cancer with or without finasteride. (See also Questions 17, 18, and 19.) 32. Does Propecia prevent prostate cancer? We don’t know. The PCPT evaluated only the 5 mg dose of finasteride, not the 1 mg dose marketed as Propecia. 33. What proportion of men in the study were African-American? About 4 percent of the men in the PCPT were African-American. PCPT investigators made strong efforts to invite African-American men to participate in this trial, but participation was voluntary and investigators did not succeed in enrolling a large number of Afr
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