Are modifiers EA, EB and EC required for the administration of Erythropoiesis Stimulating Agents (ESA)?

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Are modifiers EA, EB and EC required for the administration of Erythropoiesis Stimulating Agents (ESA)?

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Effective January 1, 2008, Medicare Part B requires that all claims submitted for non-ESRD ESA codes J0881 and J0885 to be billed with modifier EA, EB or EC.