Are QTL mapping results much affected by segregation distortion?
QTL analyses are generally conditional on the observed marker genotype data, and so results are little affected by the presence of segregation distoortion. The reconstruction of genotypes at putative QTL relies on an assumption of no segregation distortion, but with reasonably dense markers and reasonably complete genotype data, this will not be a concern. Segregation distortion may result in reduced power to identify QTL, but it should not lead to spurious evidence for QTL.
