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No. The very small sections that we test for (literally single letter changes) can mutate without any adverse effect on the individual. There is a caveat that if an entire region of the Y-chromosome has been deleted, this deleted section may include a gene as well as markers that we test for. This may occur for the P25 marker in approx. 0.025% of the male population. We do test for this marker but would report a null value if it is not detectable. If the entire section is deleted, then the AZFc gene which regulated fertility will also be deleted. Please be aware of this when ordering. If we are unable to detect the P25 marker, we shall of course inform you. Please note that this is an identical situation to the DYS464 marker in our Y-STR test.
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Are the Paternal Roots results medically informative?
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