Are there any side effects or adverse reactions to Xolair®?
Common side effects of Xolair® include a reaction at the injection site, viral infections, upper respiratory tract infection, sinusitis, headache and sore throat. These side effects were about as common in patients who received placebo injections. Several rare, yet severe side effects were reported in the original studies. They include malignancy and anaphylaxis. In the initial studies, malignancies were seen in 0.5% of patients treated with Xolair®. The rate was 0.2% in patients treated with the placebo dose. In the initial studies, anaphylaxis was seen in less than 0.1% of the patients treated with Xolair. Since Xolair® was approved in June 2003 additional reports of anaphylaxis have been reported to the FDA. Information was gathered from about 39,500 patients treated with Xolair. The serious reactions occurred in at least 1 of every 1,000 patients. The reactions these patients had included combinations of symptoms of anaphylaxis.
