Are there any specific medication safety concerns with regard to prophylaxis and treatment of bioterror-associated infections in children?
For some bioterror-related infections including anthrax, plague, and tularemia, ciprofloxacin and doxycycline are preferred or alternative treatments for children; however, specific safety concerns exist with regard to the use of these medications in this patient population. Tetracycline use in children less than 8 years of age has been associated with a negative impact on tooth development. Doxycycline carries the same warnings as tetracycline; however, it is potentially a safer alternative. Doxycycline is not thought to bind to calcium to the same degree that tetracycline does; therefore, it may cause less staining of the teeth. The administration of fluoroquinolones to children is generally not recommended due to concerns regarding potential cartilage damage and arthropathy. Clinicians caring for children in bioterror settings need to assess the risks and benefits of therapy with these medications on an individual basis; however, the significant benefits of therapy on morbidity and
Related Questions
- Are there any specific medication safety concerns with regard to prophylaxis and treatment of bioterror-associated infections in children?
- Are there any special concerns with regard to prophylaxis and treatment of bioterror-related infections in elderly patients?
- Where do children receive treatment other than medication?
