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Are there relationships between ventricular enlargement, cerebral perfusion, brain oxygen delivery, and on-going cerebral damage?

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Are there relationships between ventricular enlargement, cerebral perfusion, brain oxygen delivery, and on-going cerebral damage?

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Doppler ultrasonography has been applied in premature infants to characterize post delivery changes in arterial and venous cerebral blood flow velocities.[1] Critically low superior vena cava flow measured by Doppler ultrasonography in the first 24 hours of life has been associated with intraventricular hemorrhage in premature infants born before 30 weeks gestation.[2] Using pulsed Doppler ultrasonography, the resistive index can be measured which is a inversely related to blood flow. In older infants with established hydrocephalus, cerebral blood flow resistive index appeared to be a good indicator of increased intracranial pressure.[3] However, in a review article, the value of Doppler indices alone in predicting increased intracranial pressure was strongly questioned.[4] In a recent article, the resistive index of the anterior cerebral artery decreased significantly after CSF drainage in infants with PHH. [5] Although Doppler ultrasonography is easy to perform, its role in detecting

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