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Can a distemper vaccination lead to aggression/shivering?

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Can a distemper vaccination lead to aggression/shivering?

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My 5 1/2 month maltese got a distemper vaccination this afternoon and was acting normally until about an hour ago. We fed him dinner, let him go to the bathroom and put him in his crate for about an hour. He whimpered for awhile and then he settled down. When we let him out, he started to bite and whimper when I picked him up, and he seemed scared and was shivering. He’s relaxed right now, but he’s still shivering. Could this be a result of the shot? This is not normal behavior for him.

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