Can any one explain how adh becomes negative in the kidney?
Anti-Diuretic Hormone, or Vasopressin is a hormone secreted by the pituitary gland, which increases permeability of the distal tubules in the nephrons of the kidneys, in an attempt to increase blood osmolarity, or amount of water in your blood. When your blood contains too much water, (which can cause your RBCs to burst) the Adrenal Cortex releases Aldosterone. Aldosterone works in a negative feedback response with ADH, which makes the nephrons absorb more salt in order to lower blood osmolarity. If you were out in the dessert and your ADH levels were checked they would be very high, making your urine very concentrated, because your body is trying to absorb more water.
