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Can BRCA1 and BRCA2 mutations be inherited from either side of the family?

April 26, 2017brca1 brca2 family inherited mutations

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Can BRCA1 and BRCA2 mutations be inherited from either side of the family?

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Yes, either parent can pass along a BRCA1 or BRCA2 mutation. Therefore, it is important for clinicians to obtain a complete cancer history on both the maternal and the paternal sides of the family when assessing genetic risk.