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Can erythema nodosum and reactive arthritis be a sequel to Shigella flexneri gastroenteritis?

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Can erythema nodosum and reactive arthritis be a sequel to Shigella flexneri gastroenteritis?

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Erythema nodosum and seronegative arthritis associated with diarrhoea was previously regarded as implying the presence of inflammatory bowel disease. Recently, however, erythema nodosum has been described as a sequel to diarrhoea caused by infection with Salmonella typhimurium, Yersinia enterocolitica and Campylobacter jejuni. We report two patients in whom erythema nodosum and reactive arthritis followed acute Shigella flexneri gastroenteritis, a rare association.

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