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Can hypermethylated Wnt-antagonist genes act as biomarkers for bladder cancer?

April 26, 2017ACT biomarkers bladder cancer genes

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Can hypermethylated Wnt-antagonist genes act as biomarkers for bladder cancer?

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Original article Urakami S et al. (2006) Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. Clin Cancer Res 12: 2109–2116 PubMedDysfunction of Wnt-antagonist genes can contribute to carcinogenesis, and aberrant promoter hypermethylation of these genes has been found in bladder tumors.