Can I take phentermine if I am also on an antidepressant?
This is a question that is best answered by your primary care doctor or psychiatrist. There is a class of older antidepressants called MAO inhibitors that you definitely cannot take in combination with phentermine. For patients on the newer antidepressants, which are in more common use (e.g. Prozac, Paxil, Zoloft, Celexa, Effexor), we are not aware of any adverse interactions, and have many patients in the program who are on one of these medications and doing fine, but your doctor should still be consulted.