Can someone inherit mutations in both genes? If so, what are their risks for cancer?
A. Although uncommon, it is possible for someone to inherit a mutation in both the BRCA1 and BRCA2 genes. Because it is unusual, there is little research on the related cancer risks. Experts will often use the higher risk estimates for each cancer. For ovarian cancer experts may use risk estimates similar to estimates for people with a BRCA1 mutation and for pancreatic cancer, prostate cancer, and melanoma, experts may use estimates similar to those for people with a BRCA2 mutation. Q. My doctor recommended that I have BRCA genetic testing. I’m not sure that I want to have genetic testing, but I do want to understand more about the cancer in my family. If I do decide to have testing, how can I go about getting the test? A. Before taking a hereditary cancer genetic test such as a BRCA test, it is recommended that you speak with an expert who specializes in cancer genetics. They will evaluate your family medical history and assure the proper test is ordered and results are interpreted co
