Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes?
Paviour DC; Winterburn D; Simmonds S; Burgess G; Wilkinson L; Fox NC; Lees AJ; Jahanshahi M The Sara Koe PSP Research Centre, Institute of Neurology, London, UK. dpaviour@dementia.ion.ucl.ac.uk The frontal assessment battery (FAB) is a bedside test of executive function. It takes less than 10 minutes to administer and a low score indicates executive dysfunction. To determine whether the FAB could detect the more severe subcortical dementia that is a feature of PSP and differentiate it from other bradykinetic rigid syndromes, we studied 17 patients with progressive supranuclear palsy (PSP); 11 with multiple system atrophy (MSA) and 12 with Parkinson’s disease (PD). We compared FAB scores with the results of more detailed tests of executive and general cognitive function.FAB scores were significantly lower in PSP than in MSA or PD (p=0.