Cigarette Smoking Is a Definite Risk Factor for Myocardial Infarction and Lower Limb Arteriopathy: What About Cigarettes and Risk of Stroke?
Several studies have addressed the issue of cigarette smoking and stroke with varying associations. Bonita et al. [1986] reported a well-designed and well-conducted population-based case-control study on 132 cases of stroke identified as a part of a population-based register compared with 1,586 controls from a survey of cardiovascular risk factors conducted in the same population. In that study population, cigarette smokers had a threefold increase (odds ratio 2.9, 95% confidence interval 2.0-4.1) in the risk of stroke compared with current non-smokers. The association was slightly more pronounced in men (odds ratio 3.1, 95% confidence interval 2.0^.9) than in women (odds ratio 2.6, 95% confidence interval 1.4-4.6) but all associations were statistically significant. Moreover, there was a clear-cut dose-response relation between the number of cigarettes smoked and the risk of stroke. The risk for those smoking 1-20 cigarettes a day was 3.3 compared with nonsmokers, while the risk for h
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