Corticosteroids Question: Could you please explain if there is a difference between prednisone, decadron, and dexamethasone?
Dexamethasone is the generic form of decadron. Prednisone differs mainly in terms of potency. Prednisone is about 4-5 times as potent milligram for milligram as cortisol. Dexamethasone is about 20-25 times as powerful mg for mg. Prednisone also has slight sodium retaining potential that dexamethasone does not have. Prednisone lasts longer than cortisol but shorter than dexamethasone. Prednisone causing Osteoporosis Question: I would like to have some information by one of the doctors who answers the questions. Answer: Steroid induced osteoporosis is common and will occur with any one who takes steroids. Like most steroid side effects it depends on the dosage and the length of time. Small doses for short periods of time have negligible side effects. Larger doses or longer periods of time will thin the bones. The treatment is Vitamin D and Calcium replacement while one is taking steroids. There currently is research ongoing with Fosamax and nasal calcitonin, but it is not yet available.
