Could Nicotinamide And Vitamin E Have Synergistic Effect And Reduce Insulin Usage?
By Cameron Johnston Special to DG News MONTREAL, QC — July 11, 2001 — The combination of nicotinamide and vitamin E might have a synergistic effect in lowering daily insulin usage among newly diagnosed Type 1 diabetics. Nicotinamide is an important B-complex vitamin that is used as an intermediate agent in many pharmaceuticals. In previous studies, it has been shown to have some effect in preserving beta-cell function. Vitamin E might work at the B-cell level by reducing cytotoxicity mediated by cytokines, but it has never been shown to affect the autoimmune process that leads to the loss of B-cell function, nor does it have an impact on the insulin process. Italian investigators presented the results of a new study involving children (mean age 7.8 years) who had been diagnosed with Type 1 diabetes within the previous four weeks yesterday (July 10) at the the 6th joint meeting of the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology (ESP
