Do Cellular Heat Acclimation Responses Modulate Central Thermoregulatory Activity?

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Do Cellular Heat Acclimation Responses Modulate Central Thermoregulatory Activity?

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The classical concept of heat acclimation is of an autonomically controlled array of integrative physiological processes, improving heat tolerance. New evidence suggests that a temporal interplay between opposing autonomic and peripheral cell-originated responses, switched on by heat and autonomic stimulation of the cell membrane, and a marked increase in the stock of the inducible 70-kDa heat shock protein contribute to widening of the thermoregulatory activity span.

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