Do Precise Gels contain SDS?
No. Precise Gels do not contain SDS. SDS is used to denature proteins and surround them with a uniform net negative charge. The charges on the protein become negligible and their shape no longer has an effect such that electrophoresis is conducted purely on size. Precise Gels need to be run with SDS. The SDS included in the sample and running buffers is enough to denature the proteins and maintain them in that state throughout the run.
