Do the Monoamines in Crab pericardial Organs Play a Role in Peptide Neurosecretion?
A. BERLIND 1, I. M. COOKE 2, and MARTHA W. GOLDSTONE 3 1 The Biological Laboratories, Harvard University Cambridge, Massachusetts 02138, U.S.A.; Department of Zoology, University of California, Berkeley, California 94720, U.S.A. 2 The Biological Laboratories, Harvard University Cambridge, Massachusetts 02138, U.S.A.; Laboratoire de Neurophysiologie Cellulaire du C.N.R.S., 4, Avenue Gordon-Bennett, Paris 16 3 The Biological Laboratories, Harvard University Cambridge, Massachusetts 02138, U.S.A. 1. Pericardial organs of Libima emargmata and L. dubia were isolated, the nerves from the thoracic ganglion were stimulated electrically, and propagated electrical activity was recorded. Fluid which bathed the neurohaemal organ was assayed for cardio-excitor effects on the isolated crab heart, when necessary, made tachyphylactic to drugs. 2. Neither 10-6 M 5-hydroxytryptamine (5-HT), 10-5 M dopamine (DA), nor 10-5 M UML applied directly to the pericardial organ evoke release, nor do DA or UML alt
