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Do we need screening for thrombophilia prior to kidney transplantation?

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Do we need screening for thrombophilia prior to kidney transplantation?

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1 Department of Surgery, Transplant Division, University of Wisconsin Hospital, Madison, WI, USA and 2 Medizinische Universitätsklinik, Heidelberg, Germany Correspondence and offprint requests to: Dr Joachim Andrassy, Department of Surgery, Transplant Division, H4/747 CSC, 600 Hyland Avenue, 53792 Madison, WI, USA. Abstract Background. There is increased risk for the occurrence of deep venous thrombosis (DVT) and renovascular thrombosis after kidney transplantation. A disruption of the blood homeostasis caused by surgery and leading to clotting and bleeding malfunctions is widely accepted. However, other causes such as inherited or acquired disorders of the clotting system may further increase the risk of thrombosis. Here, we summarize and review data on possible causes, incidence and ways to prevent the occurrence of DVT and/or renovascular thrombosis after kidney transplantation. Results. The incidence of DVT after kidney transplantation is 6.2 8.3% and 25% of these patients suffer f

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