Do whole-grain oat cereals reduce the need for antihypertensive medications and improve blood pressure control?
Pins JJ; Geleva D; Keenan JM; Frazel C; O’Connor PJ; Cherney LM University of Minnesota Medical School, Minneapolis, MN 55455-0392, USA. jpins@famprac.umn.edu OBJECTIVES: Our study compared 2 whole grain oat-based cereals with 2 refined grain wheat-based cereals to determine their effects on the need for antihypertensive medications in people with high blood pressure (BP). STUDY DESIGN: This 12-week, randomized controlled parallel-group trial with = 6 weeks of voluntary follow-up was designed to investigate the antihypertensive effects of oats. After 4 weeks of baseline feeding, medication dose was maintained or reduced by half or completely throughout the middle 4 weeks of the study. In the final 4 weeks, participants continued cereal consumption; medication was adjusted according to the protocol. POPULATION: Men and women (n = 88) being treated for hypertension with a mean baseline BP below 160/100. OUTCOMES MEASURED: Primary study outcomes included change in SBP and DBP as well as a
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