Does Acetaminophen Potentiate the Gastroduodenal Mucosal Injury of Aspirin?
A Prospective, Randomized, Pilot Study. This study is sponsored by Pfizer, Inc and is conducted by Dr. Jay Goldstein We are looking for healthy volunteers. The study duration is approximately 3-4 weeks. Subjects will be randomized to 3 treatment arms, Acetaminophen + Aspirin, Acetaminophen + placebo, Aspirin + Placebo. A Randomized, Open-Label, Comparative 3-way Crossover Study of 24-hour Intragastric pH profile of Once Daily Oral Administration of Esomeprazole 40 mg, Lansoprazole 30 mg, and Pantoprazole 40 mg at Steady State in Hispanic Patients with Symptomatic GERD This study is sponsored by AstraZeneca and conducted by Dr. Jay Goldstein. This study is being done to compare the efficacy of three PPI’s in controlling stomach acid in the Hispanic population. Eligible subjects need to be diagnosed with GERD and be of Hispanic origin. Qualified subjects will be administered one of three chosen PPI’s and will have a subsequent 24-hour pH probe placed to measure acid in the esophagus. Sub