Does anyone 5 years of age or older need to receive Hib vaccine?
There are few data on the efficacy of Hib vaccine in persons 5 years of age or older. ACIP recommends consideration of Hib vaccination for unvaccinated persons 5 years of age and older with anatomic or functional asplenia, sickle-cell anemia, or HIV infection (MMWR 1993;42[RR-4]:8; MMWR 1991;40[RR-12]:29). A single dose of any licensed conjugate vaccine is probably sufficient in most cases (using the dose recommended by the manufacturer for a child). The 2000 AAP Red Book suggests 2 doses separated by 1-2 months for persons with HIV infection or IgG2 immune deficiency.