Does creatine supplementation influence mental acuity in humans?
The study examined the effect of creatine supplementation (5 grams/day for six weeks) on the ability to perform two cognitive tests, the Raven’s Advanced Progressive Matrices (RAPMs) and Weschler Auditory Backward Digit Span (BDS). These tasks are designed to test non-verbal intelligence (IQ) and verbal memory capacity (short-term memory), respectively. The authors of the study also chose 45 vegetarians and vegans as experimental subjects. This group of individuals was chosen since their dietary intake of creatine, which was negligible, would not interfere with the amount of creatine administered during the course of the study.