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Does dexamethasone suppress the ACTH response in preterm babies?

April 26, 2017ACTH babies dexamethasone preterm Response suppress

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Does dexamethasone suppress the ACTH response in preterm babies?

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Tests of adrenal stimulation with adrenocorticotrophic hormone (ACTH) were performed before and after commencing dexamethasone treatment in 12 infants. All except one of the tests performed showed the expected twofold rise in serum cortisol, suggesting that in this group of premature babies dexamethasone did not suppress the adrenal response.