Does domperidone work to increase milk supply?
There is an abundance of clinical experience and anecdotal reports of improved milk supply with domperidone over the last 30 years. There are now 5 studies (albeit each with small numbers of subjects) which demonstrate clinically insignificant concentrations of domperidone in human milk, no side effects in infants, minimal to no side effects in mothers, and increased milk supply in most mothers. (3-7) Is domperidone safe? The American Academy of Pediatrics (AAP) lists domperidone as a drug compatible with breastfeeding. (8) It is also listed in pharmacy resources such as DrugDex and MicroMedex, and as a preferred galactogogue by the Academy of Breastfeeding Medicine.(9) According to the manufacturer, adverse side effects include very rare allergic reactions; very rare extrapyramidal side effects; rare intestinal symptoms including cramps; rare galactorrhea (milk production), gynecomastia (increased breast size) and amenorrhea (lack of menstrual periods). There have been several publish
