Does FNA Improve the Accuracy of Endoscopic Ultrasound in Evaluating Mediastinal Lymphadenopathy?
Srinivas R. Puli, MD, Jyotsna Batapati Krishna Reddy, MBBS, Matthew L. Bechtold, MD, Jamal A. Ibdah, MD, Mainor R. Antillon, MD., *Department of Gastroenterology and Hepatology, University of Missouri-Columbia, Columbia, MO.Purpose: The published data on accuracy of endoscopic ultrasound (EUS) to differentiate inflammatory from neoplastic process in a lymph node has been varied. This differentiation is crucial for appropriate therapy. The impact of EUS-fine needle aspiration (FNA) in the evaluation of mediastinal lymphadenopathy is not clear.Aim: To evaluate the accuracy of EUS alone and EUS with FNA in evaluating mediastinal lymphadenopathyMethods: Study Selection Criteria: Only EUS and EUS-FNA studies confirmed by surgery or with prolonged follow-up were selected.Data collection & extraction: Articles were searched in Medline, Pubmed, Ovid journals, CINAH, and Cochrane controlled trials registry. Two reviewers independently searched and extracted data. The differences were resolved b
