Does naltrexone have side effects?
In general, naltrexone is well tolerated with no severe side effects. In the largest study, the most common side effects of naltrexone affected only a minority of people and included the following generally short-lived symptoms: nausea (10%), headache (7%), dizziness (4%), fatigue (4%), insomnia (3%), anxiety (2%) and sleepiness (2%). Naltrexone medication is a passive substance with no stimulating or tranquilizing effects. Further, naltrexone does not interfere with other medical and psychiatric medications, such as anti-depressants (e.g., Celexa®, Lexapro®, Luvox®, Paxil®, Prozac®, Zoloft® and Effexor® or Welbutrin®), mood stabilizers and other tranquilizing medications. The only contraindication to the use of naltrexone is opiate or opioid (analgesic or pain-killing) medication. Naltrexone is likely to have little impact on other medications patients commonly use, such as antibiotics, non-opioid analgesics, like aspirin, acetaminophen and ibuprofen, and allergy medications.
