Does Screening for HIV in Asymptomatic Pregnant Women Reduce Mother-to-Child Transmission or Premature Death and Disability?
We identified no randomized trials or observational studies comparing clinical outcomes from screening or not screening pregnant patients in the general population. Although the number of infants with perinatally acquired HIV transmission has markedly declined in the U.S., this is probably due to a combination of increased screening during pregnancy and increased development and acceptance of interventions to prevent transmission, and some HIV-positive women may have been identified before their pregnancy.5, 18 We identified no studies estimating the relative impact of these factors on transmission rates.
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