Does SUBOXONE or METHADONE just substitute one dependence for another?
All opioids can cause physical dependence. SUBOXONE belongs to a class of opioids called “partial opiod agonists.” As a partial agonist, buprenorphine appears to produce less physical dependence, limited euphoria, and less potential for abuse compared with a full agonist, eg, heroin, oxycodone, and hydrocodone. METHADONE is used in more severe cases of opiate addiction where a partial opioid agonist will not suffice. The principals for treatment are the same for both medications but METHADONE is used in more advanced cases. SUBOXONE and METHADONE have potential for abuse and produce dependence of the opioid type. SUBOXONE tends to show a milder withdrawal syndrome than full agonists.
