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Does the use of topical transexamic acid in cardiac surgery reduce the incidence of post-operative mediastinal bleeding?

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Does the use of topical transexamic acid in cardiac surgery reduce the incidence of post-operative mediastinal bleeding?

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Best Evidence Topics or BETs are designed for use in Emergency Medicine, where many of the questions raised by the varied clinical workload are not addressed by high quality clinical trials. BETs allow the inclusion of lower quality evidence, by listing weaknesses of papers included for evaluation. The same rigorous approach to finding papers is taken. It should be noted, however, that BETs are not systematic reviews of the sort conducted by the Cochrane Collaboration, and therefore include only published evidence.

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