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Has LODOSYN been associated with Neuroleptic Malignant Syndrome (NMS)?

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Has LODOSYN been associated with Neuroleptic Malignant Syndrome (NMS)?

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Sporadic cases of a symptom complex resembling NMS have been reported in association with dose reductions or withdrawal of certain antiparkinsonian agents such as levodopa, SINEMET (Carbidopa-Levodopa), or SINEMET CR (Carbidopa-Levodopa) Sustained-Release. Therefore, patients should be observed carefully when the dosage of levodopa is reduced abruptly or discontinued, especially if the patient is receiving neuroleptics. Please refer to the full prescribing information.

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