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How are changes in chromosome 8 related to health conditions?

April 26, 2017Autosomes changes CHROMOSOME chromosomes Conditions Health submetacentric

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How are changes in chromosome 8 related to health conditions?

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Rearrangements (translocations) of genetic material between chromosome 8 and other chromosomes have been associated with several types of cancer. For example, Burkitt lymphoma (a cancer of white blood cells that occurs most often in children and young adults) can be caused by a translocation between chromosomes 8 and 14. This translocation, written t(8;14)(q24;q32), leads to continuous cell division without control or order, which likely contributes to the development of Burkitt lymphoma. Less frequently, Burkitt lymphoma can be caused by translocations between chromosomes 8 and 2 or chromosomes 8 and 22.