How are InterPro entries mapped to GO terms?
See this extract from our user manual: The assignment of GO terms to InterPro entries was done manually by reading the abstract of the entries and annotation of proteins in the protein match table for each entry. An appropriate GO term for an entry is one which applies to the whole protein. The GO terms associated with an InterPro entry applies to all proteins with true hits to the signatures in that entry. The assignments are incomplete and are ongoing due to the dynamic nature of the GO project. Some entries could be mapped to very low level (specific) GO terms, while entries describing wider families or common domains were mapped to higher level terms or could not be mapped at all. If the protein matchlist is completely uncharacterised/unannotated, then no GO terms are assigned. If there are some UniProt matches but they are annotated as hypothetical because the function is not known then they are mapped to the GO term molecular function unknown.
- Im in the process of updating the InterPro to GO mappings that I have stored locally and noticed that some InterPro motifs that previously had GO terms associated no longer do so, is this correct?
- Whats the difference between the terms UV mapped, Implicit and Parametric?
- How are InterPro entries mapped to GO terms?