How are intralipids given?
Intralipids are diluted in saline solution usually just before they are given (often by injecting the contents of a bag of concentrated intralipid into a much larger bag (or IV bottle) of saline e.g., starting with a 500ml IV bag of saline, 100mls is withdrawn by syringe through the ‘port’ and discarded so that 100mls of intralipid can be injected before shaking the bag gently to mix it). You need to have a cannula fitted in the back of your hand or in the crook of your elbow, and then the intralipid is infused in by IV over 1-2 hours. Intralipid is more viscous than IVIG so a 22 guage blue, 20 gauge pink (or larger 18 gauge green) cannula is normally used. The dose does not tend to vary by the weight of the patient as it is less critical than for IVIG because its much cheaper. Dr Gorgy, SIRM and Care tend to use a dose of 100mls 20% intralipids diluted in 200-500mls of saline but other clinics may use lower or higher doses, and I have heard that some clinics overseas give intralipids
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