How are recent advances in siRNA technologies and methodologies revolutionizing the functional analysis of genes and proteins?
High-content cellular analysis (HCA) is now the key methodology applied to large scale siRNA screens. High-throughput RNA interference methods and HCA is a match made in heaven. This powerful combination of technologies which couple the specificity of the latest generation of siRNA chemistries with the unmatched analytical power of HCS for measuring phenotypic changes associated with gene knockdown provide an unparalleled opportunity for detailed pathway mapping. GE is committed to advancing high-content analysis for cell-based drug discovery and research, and we offer highly attractive choices for scientists seeking exceptional imaging capability for a breadth of high-content cellular analysis assays. How are advancements in throughput methodologies allowing large scale RNAi screens to be applied to mammalian cells? The throughput and automation of HCS now provides the means to run genome scale RNAi that would have been impracticable or even impossible only a few years ago. Data from
