How are scientists at Sanford Burnham Medical Research Institute using stem cells to understand disease?
Here at the Institute, researchers are actively pursuing cures and treatments to numerous diseases through embryonic stem cell research. Dr. Robert Oshima’s lab differentiates embryonic stem cells to more limited-capacity stem cells, called trophoblast stem cells. These cells can form cell types found in the placenta, and could be used to treat placental defects that affect nearly 3% of pregnancies. Scientists in Dr. Mark Mercola’s lab hope to use heart cells (cardiomyocytes) derived from embryonic stem cells to treat heart-related ailments. The cardiomyocytes spontaneously beat outside of the body, and could be used to treat heart attacks (myocardial infarction) and multiple forms of cardiac failure. Dr. Evan Snyder’s lab differentiates embryonic stem cells into neural stem cells with untold potential for treating neurological disorders. Researchers benefit from access to Sanford Burnham Institute’s Stem Cell Core Facility and work closely with scientists at other organizations.
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