How big is the error in size distribution?
As Brownian motion is a random process, even with the most perfectly monodisperse sample, the NanoSight system will detect a slight breadth to the distribution. The longer that a sample is analysed for, the smaller this breadth becomes. To try and negate the random effect of Brownian motion, the NTA Software has a modal curve fit function. After analysis, it is possible to use this feature to try and negate the effect that the randomness of Brownian motion has upon the size distribution.