How can a male be neutered without causing feminization?
One can cause the gonads to dramatically reduce androgen production by shutting down the output of LH and FSH from the pituitary gland. This can be done one of two ways: • Introducing consistently large quantities of any estrogen or progesterone. Progesterone does not have a feminizing effect, so one could use medroxyprogesterone acetate. This has been demonstrated to work on males with severe behavioral disorders exacerbated by androgens (read: serial rapists), who were given the choice of taking periodic shots or remaining in prison. The sustained-release injectable preparation is easier on the liver than orally delivered tablets, but one should first try the tablets for a month or two to be sure there is not an allergic reaction. Be aware that there are annoying and dangerous adverse effects with progesterones, ranging from severe mood swings to blood clotting disorders. • Alternatively, one can use a GnRH agonist. This is a more elegant solution, and has fewer adverse affects than
