How can I know that using a high concentration minoxidil solution and/or lotion isn’t an overdose and/or won’t be counterproductive to hair growth?
A. Minoxidil has to have a serum concentration of 20 ng/mL to have any hemodynamic or other systemic effect in the human body. Allowing for 1.7% absorption of minoxidil from topical application, a 2% minoxidil solution will result in 0.6 ng/ mL and a 5% minoxidil solution will result in 1.2 ng / mL of minoxidil in the serum. So, there is more than a 16-fold safety margin from the use of 5% topical minoxidil and a 5-fold safety margin with the use of a 15% topical minoxidil solution.
Related Questions
- If you put benzyl nicotinate into any high concentration minoxidil gel or lotion, wouldn the resulting gel or lotion absorb like the Xandrox® 12.5% lotion?
- If more minoxidil absorbs into the scalp with the new 12.5% minoxidil solution than with a lotion, cream or gel, why do you still offer Xandrox 12.5% lotion®?
- How can I know that using a high concentration minoxidil solution and/or lotion isn’t an overdose and/or won’t be counterproductive to hair growth?