How can the vicious-circle of dysfunctioning macrophage activation be interrupted?
The answer to this question lies in the inhibition of the pro-inflammatory macrophage activation. In this respect, the correction of an oxidative stress situation is crucial. For this reason, it seems imperative to remove such a deficiency. We have dealt with this problem in a prelimanary study on AIDS preventions for HI virus carriers.(26) Here, we want to mention only the possibility of cortisone inhibition by means of glycosaminoglycans (GAGs), such as chondroitinsulphate which play an important role in the treatment of arthrosis and osteoporosis.(27) In conclusion, we are of the same opinion as Root-Bernstein that the decision taken at the time that HI viruses are the sole decisive causative factor for AIDS considering the other risk factors as co-factors was rash and incorrect in retrospect.(28) According to our opinion, it is the sum of the risk factors which causes a severe stress-induced deficiency of the T-cell related immune reactions which in turn lead to the release of a la
