How common are BRCA1 and BRCA2 mutations in the general population?

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How common are BRCA1 and BRCA2 mutations in the general population?

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Inherited mutations in BRCA1 and BRCA2 are relatively uncommon in the general population. The carrier frequency is estimated to range from 1 in 300 to 1 in 800.1,3 Certain ethnic groups have been shown to have a higher carrier frequency (e.g., 1 in 40 individuals of Ashkenazi Jewish descent).

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Inherited mutations in BRCA1 and BRCA2 are relatively uncommon in the general population. The carrier frequency is estimated to range from 1 in 300 to 1 in 800. 1 , 3 Certain ethnic groups have been shown to have a higher carrier frequency (e.g., 1 in 40 individuals of Ashkenazi Jewish descent).

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